Pueblo County is located in the south central part of Colorado. In 2017, Pueblo County experienced an age-adjusted overdose death rate of 32.8 per 100,000 residents, nearly twice the state rate. The Pueblo Department of Public Health and Environment (PDPHE) will work with the Substance Use Response Ecosystem (SURE) members, behavioral health agencies, partners within the county Law Enforcement Assisted Diversion (LEAD) program, and others to bring together necessary expertise and systems to allow robust data sharing and analysis to determine whether current strategies to combat the drug epidemic are working and, if not, to devise other strategies in concert with their partners. Data generated as part of this project will be used by multiple groups such as the Community Health Improvement Plan (CHIP) partners to track and guide efforts occurring at all phases and levels of the continuum of community health. PDPHE will convene a stakeholder group tasked with identifying data points, reviewing data, and providing context to interpret and supplement collected data points. Data sources include, but are not limited to, mortality data points, including total drug poisoning deaths and opioid-related overdose deaths; law enforcement data points, including number of jail inmates identified as homeless and drug arrest data; emergency department data points; Narcan data; needle exchange data points; MAT data points; as well as data collected from fire and EMS, public health, and behavioral health systems.